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Ephedrine is an adrenergic drug that works by stimulating alpha
-and beta receptors thus causing the release of norepinephrine.
-Alpha and beta receptors exist in the sympathetic nervous system,
-(fight or flight) and stimulation causes increased heart rate,
-bronchodilation, and vasoconstriction.
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Ephedra's main active medical ingredients are the alkaloids ephedrine and pseudoephedrine. The ephedras also contain various tannins and related chemicals.The stem contains 1-3% total alkaloids, with
ephedrine accounting for 30-90% of this total. The concentrations of these alkaloids depends upon the particular species of ephedra used.
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Ephedrine is the oral form of Epinephrine, or adrenaline. It was
-once a commonly prescribed drug for asthma, but newer drugs in the
-xanthine class have less side effects.
-Ephedrine is rela
ted to pseudoephedrine which was designed as a
-decongestant with less undesirable effects.
-Ephedra is a Chinese herb that's been used for centuries to treat
-asthma
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Ephedrine alkaloids are amphetamine-like compounds used in OTC and prescription drugs with potentially lethal stimulant effects on the central nervous system and heart. The FDA has received more than
800 reports of adverse effects associated with use of products containing ephedrine alkaloid since 1994. These serious adverse effects, include hypertension (elevated blood pressure), palpitations (ra
pid heart rate), neurophathy (nerve damage), myopathy (muscle injury), psychosis, stroke, memory loss, heart rate irregularities, insomnia, nervousness, tremors, seizures, heart attacks, and death. Th
e agency has proposed to prohibit the marketing of dietary supplements containing 8 milligrams or more of ephedrine alkaloids per serving.
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Recently, the FDA has called for strict limits on the recommended dose and proposed new labeling of products containing ephedrine. The FDA¡¦s proposal would prohibit the marketing of dietary supplement
s containing 8 milligrams or more of ephedrine alkaloids per serving, with warnings against using more than 24 mg per day and using the product for more than SEVEN DAYS. Any such product with claims e
ncouraging short-term excessive intake would be required to list the following statement on its label: ¡§Taking more than the recommended serving may result in heart attack, stroke, seizure or death.¡¨
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What is ephedrine? Ephedrine (e-fed¡¦rin) a-methylamino-l phenyl-l propanol, is an alkaloid from the leaves of Ephededra equisetina, E. Sinica, and other species (family Gnetaceae). It is also called E
phedra & Ma Huang, the plant source for the Alkaloid ephedrine. Indigenous to China, India and parts of SoutheastAsia . Products containing ephedrine extracts have according to the FDA, caused hundred
s of illnesses, including heart attacks, seizures, strokes and even 15 reported deaths. They are amphetamine-like compounds with powerful and potentially lethal stimulant effects on the central nervou
s system and the heart.
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