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How should this medicine be used?

Antihistamines are used to relieve or prevent the symptoms of your medical problem. Take them only as directed. Do not take more of them and do not take them more often than recommended on the label, unless otherwise directed by your doctor. To do so may increase the chance of side effects.

DosingˇX

- The dose of an antihistamine will be different for different patients. Follow y ur doctor's orders or the directions on the label. The following information includes only the average doses of antihistamines. If your dose is different, do not change it unless your doctor tells you to do so.

Possible Side Effect

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they seek medical attention immediately.

Check wi th your doctor immediately if any of the following side effects occur:

Incidence rare
- Chest tightness ; feeling of warmth, redness of the face, neck, arms and occasionally, upper ches t; large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs; shortness of breath, difficult or labored breathing

What is this medicine

Fexofenadine (fex-oh-FEN-a-deen) is an antihistamine. It is used to relieve the symptoms of hay fever and hives of the skin.

Antihistamines work by preventing the effects of a substance calle d histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes. Also, in some persons histamine can close up the bronchial tubes (air passages of the lu ngs) and make breathing difficult. Histamine can also cause some persons to have hives, with severe itching of the skin.

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Drug Interactions

You should avoid drinking alcohol or taking sedatives, tranquilizers, sleeping pills, or muscle relaxants while using Zyrtec. They can lead to increased drowsiness and reduced mental alertness. Among the products to avoid are the following:

- Antidepressants such as Tofranil, Elavil, Ludiomil, and Anafranil
- Muscle relaxants such as Valium and Soma
- Pain-relieving narcotics s uch as codeine, Demerol, and Percocet
- Sedatives such as Nembutal, Seconal, and phenobarbital
- Sleeping pills such as Halcion, Restoril, and Ambien
- High doses of theophylline (Theo- Dur)

Other medical problems

PregnancyˇXIn animal studies, this medicine did not cause birth defects but did cause a decrease in weight of the infant. Discuss with your doctor whether or not you should continue to use this medici e if you become pregnant.

Breast-feedingˇXIt is not known whether fexofenadine passes into breast milk. Although most medicines pass into breast milk in small amounts, many of them may be use safely while breast-feeding. Mothers who are taking this medicine and who wish to breast-feed should discuss this with their doctor.

What special precautions should I follow?

Before you have any skin tests for allergies, tell the doctor in charge that you are taking this medicine. The results of the test may be affected by this medicine.

When taking antihistamines on a regular basis, make sure your doctor knows if you are taking large amounts of aspirin at the same time (as for arthritis or rheumatism). Effects of too much aspirin, such as ringing in the ears, may be covered up by the antihistamine.

- Antihistamines will add to the effects of alcohol and other CNS depressants (medicines that slow down the nervous system, possibly causing drowsines s).


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