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Zyban Rx Information

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How should you take this medication?
Treatment with this drug begins while you are still smoking. Zyban needs about a week to reach an effective level in your body; so to improve your chance of success, you should not attempt to quit unt il the second week of treatment. Set a firm date for quitting. If you are still smoking after that date, your odds of breaking the habit will be worse. You should keep taking Zyban for 7 to 12 weeks.

You can use nicotine patches along with Zyban. However, combining the two treatments can raise your blood pressure, so it's important to tell your doctor if you plan to use both. Do not smok e while using a patch, because too much nicotine can cause serious side effects.

Overdosage
It is especially important to check with your doctor before combining Zyban with the following:

- Alcohol
- Amantadine (Symmetrel)
- Antidepressants such as Norpramin, Pamelor, Pa xil, Prozac, Tofranil, and Zoloft
- Beta blockers (heart and blood pressure medications) such as Inderal, Lopressor, and Tenormin
- Carbamazepine (Tegretol)
- Cimetidine (Tagamet)
- Cyclophosphamide (Cytoxan)
- Heart-stabilizing drugs such as Rythmol and Tambocor
- Levodopa (Dopar, Larodopa, Sinemet)
- Major tranquilizers such as Haldol, Risperdal and Thorazine < br> - MAO inhibitors such as the antidepressants Nardil and Parnate
- Orphenadrine (Norflex)
- Phenobarbital
- Phenytoin (Dilantin)

Significant Interactions:
When you are taking Zyban, it is especially important that your health care professional know if you are taking any of the following:

- Tricyclic antidepressants (amitriptyline [e.g., Elavil ], amoxapine [e.g., Asendin], clomipramine [e.g., Anafranil], desipramine [e.g., Pertofrane], doxepin [e.g., Sinequan], imipramine [e.g., Tofranil], nortriptyline [e.g., Aventyl], protriptyline [e.g., Vivactil], trimipramine [e.g., Surmontil]) or
-
- Monoamine oxidase (MAO) inhibitor activity (isocarboxazid [e.g., Marplan], phenelzine [e.g., Nardil], procarbazine [e.g., Matulane], selegi line [e.g., Eldepryl], tranylcypromine [e.g., Parnate])— Do not take Zyban while you are taking or within 14 days of taking an MAO inhibitor

Before Taking This Medicine
Children—This medicine has been tested in a very small number of patients 6 to 16 years of age and has not been shown to cause different side effects or problems in children than it does in adults. M re testing is needed to decide whether Zyban is safe and effective for use in children.

What is this Drug
Zyban is a pharmaceutical, prescription antidepressant which acts directly on the brain and other nerve cells. It is also used to treat ADHD (Attention Deficit Disorder), Bipolar depression, chronic f atigue syndrome, cocaine addiction, nicotine addiction, and lower back pain.

Zyban generally comes in 75mg and 100mg tablets. A sustained released form (Wellbutrin SR) comes in 100mg (blue), 150mg (purple), and 200mg (light pink) tablets. A new Wellbutrin XL comes in 150 & 300mg tablets (creamy white to pale yellow).

It has been associated with possible liver and kidney damage as well as seizures in .4% of the population.

Precautions while Using this Medicine
Drinking of alcoholic beverages should be limited or avoided, if possible, while taking Zyban. This will help prevent seizures.

This medicine may cause some people to feel a false sense of we ll-being, or to become drowsy, dizzy, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerou s if you are dizzy or are not alert and clearheaded.

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