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Symptoms of overdose may include:
There is no report for massive overdose of Xenical. Although the drug seems relatively harmless, any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention.

How should this medicine be used?
Take a capsule of Xenical during, or up to 1 hour after, each main meal. You should follow a nutritionally balanced, low-calorie diet that provides no more than 30 percent of its calories from fat. If you miss a meal, or the meal contains no fat, you can skip the accompanying dose of Xenical.

special dietary instructions
Follow the diet program your doctor has given you. You should evenly divide your daily intake of fat, carbohydrates, and protein over three main meals. If Xenical is taken with a meal very high in fat (30% total daily calories from fat), you may experience more side effects from the medication.

Xenical blocks your body's uptake of some fat-soluble vitamins and beta carotene. Therefore, wh en you use Xenical you should take a daily multivitamin supplement that contains vitamins A, E, K, and beta-carotene. Take the vitamin once a day, 2 hours before or 2 hours after taking Xenical, or ta ke the vitamin at bedtime.

Other Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to c hange the dose, or other precautions may be necessary. When you are taking Xenical, it is especially important that your health care professional know if you are taking the following:

- Warfa rin—Xenical may decrease the absorption of vitamin K and may change your bleeding time

What special precautions should I follow?
.For patients with diabetes: Weight loss may result in an improvement in your condition, and your doctor may need to change your dose of oral diabetes medicine or insulin.

Visit your doctor on a regular basis to check your progressto make sure that this medicine is working properly and to check for unwanted effects

Possible Side Effect
More common side effects may include:
- Abdominal discomfort or pain, anxiety, arthritis, back pain, diarrhea, dizziness, earache, fatigue, fatty or oily stools, fecal urgency or incontinence, fl u, gas with fecal discharge, gum problems, headache, increased defecation, menstrual problems, muscle pain, nausea, oily discharge, rectal discomfort or pain, respiratory tract infections, skin rash, sleep problems, tooth problems, urinary tract infections, vaginal inflammation, vomiting

Less common side effects may include:
- Dry skin, ear/nose/throat problems, joint disorders
< br> Side effects that usually occur after the first year of treatment with Xenical include: depression, leg pain, swollen feet, and tendonitis.

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