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Missing Dose

Iit is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose of either the ointment or oral medication to make up for a missed one.

Other medical problems

Herpes infection of the genitals can be caught from or spread to your partner during any sexual activity. Even though you may get herpes if your partner has no symptoms, the infection is more likely t o be spread if sores are present. This is true until the sores are completely healed and the scabs have fallen off. Therefore, it is best to avoid any sexual activity if either you or your sexual part ner has any symptoms of herpes. The use of a latex condom (ˇ§rubberˇ¨') may help prevent the spread of herpes. However, spermicidal (sperm-killing) jelly or a diaphragm will probably not help.

Possible food and drug interactions when taking this medication

Tell you doctor if you are taking any of the following:
- Deferoxamine (e.g., Desferal) (with long-term use) or
- Gold salts (medicine for arthritis) or
- Inflammation or pain medicine

Side Effects of This Medicine

Oral: (GI side effects reduced if take with meals)
Short-term therapy: nausea/vomiting, diarrhea, headache, dizziness, fatigue, skin rash, edema. inguinal adenopahty, anorexia, leg pain, medicatio n taste, sore throat.
Long-term: nausea/vomiting, diarrhea, headache, vertigo, insomina, irritability, depression, skin rash, acne. accelerated hair loss, arthralgia, fever, palpitations, sore thr oat, muscle cramps, mestrual abnormalities, lyphadenopathy.

Precautions while Using this Medicine

Before taking acyclovir,

- tell your doctor and pharmacist if you are allergic to acyclovir, valacyclovir (Valtrex), or any other drugs.
- tell your doctor and pharmacist what prescripti on and nonprescription medications you are taking, especially probenecid (Benemid), zidovudine (Retrovir, AZT), and vitamins.
- tell your doctor if you have or have ever had kidney disease, probl ems with your immune system, human immunodeficiency virus infection (HIV), or acquired immunodeficiency syndrome (AIDS).
- tell your doctor if you are pregnant, plan to become pregnant, or are br east-feeding. If you become pregnant while taking acyclovir, call your doctor.

Why is this medication prescribed?

Acyclovir (ay-SYE-kloe-veer) belongs to the family of medicines called antivirals. Antivirals are used to treat infections caused by viruses. Usually they work for only one kind or group of virus infe ctions.

Topical acyclovir is used to treat the symptoms of herpes simplex virus infections of the skin, mucous membranes, and genitals (sex organs). Although topical acyclovir will not cure herpes simplex, it may help relieve the pain and discomfort and may help the sores (if any) heal faster. Topical acyclovir may also be used for other conditions as determined by your doctor.

Acyclovir is available only with your doctor's prescription, in the following dosage forms:

Topical
Cream (Canada)
Ointment (U.S. and Canada)


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