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Side Effects

This medication may cause stomach upset, loss of appetite, nausea, vomiting, diarrhea, headache, dizziness or weakness. These effects should disappear in a few days as your body adjusts to the medicat ion. If they persist or become worse, inform your doctor. Notify your doctor if you experience: numbness or tingling of the hands or feet, leg pain, sore throat, skin rash, change in the amount of uri ne. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. I f you notice other effects not listed above, contact your doctor or pharmacist.

Proper Use of This Medicine

Genital herpes (initial): 200mg po q 4 hours 5 times/day X 10 days
Genital herpes (recurrent or suppressive therapy): 400mg 2 times/day for up to 12 months, then re-evaluate.
Herpes zoster: 80 0mg 5 times/day X 7-10 days
Sever HZV or complications: 5-10mg/kg IV q 8 hours X 7-10 days. Administer at constant rate over 1 hour.

Special warnings about this medication

If you are or will be breast-feeing while you are using this medicine, check with your doctor or pharmacist to discuss the risks to your baby.

What should I do if I forget a dose?

If you are using tablets, capsules, or liquid, take the missed dose as soon as you remember it and take any remaining doses for that day at evenly spaced intervals.

If you are using ointment, apply it as soon as you remember and apply further doses at your regular interval (e.g., every 3 hours) until you go to bed.

However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose of either the ointment or oral medication to make up for a missed one.

Other medical problems

This medication should be used cautiously during pregnancy only if clearly needed. It is not known if this medication appears in breast milk. Consult with your doctor before breast-feeding.
Avoid s exual activity while signs and symptoms of genital herpes are present to prevent infecting your partner. Inform your doctor if this medication does not appear to decrease the frequency or severity of recurrent infections.

Drug Interactions

Inform your doctor if you are taking any of the following:
- Lithium (e.g., Lithane) or
- Methotrexate or
- Other medicine for infection or
- Penicillamine (e.g., Cuprimine)


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